Journal article
Do long-chain n-3 fatty acids reduce arterial stiffness? A meta-analysis of randomised controlled trials
MP Pase, NA Grima, J Sarris
British Journal of Nutrition | Published : 2011
Abstract
Fish oils, rich in long-chain n-3 PUFA, are known to reduce various risk factors for CVD. However, conclusive evidence regarding the benefits of n-3 on arterial stiffness, a risk factor for CVD, has not yet been established. Consequently, we conducted the first study aimed to quantify the effects of n-3 supplementation on arterial stiffness through meta-analysis. Multiple databases and clinical trial registries were systematically searched up until September 2010 for randomised and controlled adult human clinical trials to investigate the effects of long-chain n-3 fatty acids on arterial stiffness. No limits were set on dosage sizes or sample characteristics. A total of ten n-3 trials met th..
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Grants
Awarded by Australian National Health and Medical Research Council
Funding Acknowledgements
The authors declare no conflicts of interest. M. P. P. and N. A. G. are each funded by an Australian Postgraduate Award. J. S. is funded by an Australian National Health and Medical Research Council Fellowship (ID 628875). The authors' responsibilities were as follows: all authors were responsible for the research design, conduct, data analysis and writing of the manuscript.